Turning a tumor’s ‘shield’ into a weapon against itself

Tumor cells are “cunning,” according to Peter Yingxiao Wang. They have a nefarious way of evading the human immune responses that fight back against these cancerous invaders. Tumor cells express programmed death-ligand 1 (PD-L1) molecules, which work like a defensive shield that suppresses our immune cells, posing a hurdle for targeted cancer immunotherapies.

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