New study highlights senescent cell removal mechanisms of canagliflozin, a sodium glucose co-transporter 2 inhibitor

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases. The removal of senescent cells, also known as “senolysis,” can therefore serve as an effective strategy against aging-related diseases. Now, researchers from Japan have uncovered novel molecular mechanisms underlying the senolytic effects of canagliflozin—a sodium glucose co-transporter 2 inhibitor used to control blood glucose levels.

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