New drug candidates targeting blood clots developed through computer-aided drug design

A team of Vanderbilt researchers has created a new series of drug candidates against a hard-to-target receptor involved in the formation of blood clots. The research, spearheaded by the labs of Jens Meiler, research professor of chemistry, Craig Lindsley, Executive Director of Warren Center for Neuroscience Drug Discovery and professor of pharmacology, and Heidi Hamm, the Aileen M. Lange and Annie Mary Lyle Professor of Cardiovascular Research and professor of pharmacology, was published in ACS Pharmacology and Translational Science in March 2024.

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