Written by Cancer poses significant challenges due to the development of resistance and the likelihood of relapse. Resistance may arise from permanent genetic changes in cancer cells or non-genetic alterations in cancer cell behavior induced by treatment. Standard of care in cancer treatments typically involves administering the maximum tolerated dose of a drug to eradicate drug-sensitive cells effectively. However, this approach often fails in the long term because drug-resistant cancer cells can grow more rapidly when all drug-sensitive cancer cells are killed off.
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