Written by Tumor protein P53 (TP53) plays an important role in suppressing the growth of tumors. Mutations in the gene for TP53 can have a disastrous effect, hampering the body’s ability to fight tumors and even encouraging their growth. Because these are the most common mutations in cancers, TP53 has long been an interesting therapeutic target. However, efforts to destroy the mutant protein have been hampered by the difficulty of finding a way to bind to it.
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