A single dose of typhoid conjugate vaccine (TCV) offers safe, effective protection against typhoid two years after vaccination in all children, and sustained protection for older children at three to five years post immunization, according to a report by researchers at the Oxford Vaccine Group and the International Center for Diarrheal Disease Research, Bangladesh (icddr,b). But it also shows a decline in protection at the later timepoints among children vaccinated at younger ages.
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