Scans show brain’s estrogen activity changes during menopause

The transition to menopause is marked by a progressively higher density of estrogen receptors (ER) on brain cells, a measure that remains elevated in women up to their mid-sixties, according to a new brain imaging study led by researchers at Weill Cornell Medicine. In addition to revealing new evidence of the brain’s response to this major life change, the study pioneers the use of positron emission tomography (PET) imaging as a tool for studying estrogen activity in the brain, which hasn’t been possible to track until now.

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