Individuals who display exceptional longevity provide evidence that humans can live longer, healthier lives. Centenarians (greater than 100 years of age) provide a unique lens through which to study longevity and healthy aging, as they have the capacity to delay or escape aging-related diseases such as cancer, cardiovascular disease and Alzheimer’s disease, while markedly avoiding disability. Problematically, models of human aging and resilience to disease that allow for the testing of potential interventions are virtually non-existent.
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