Immune cell transformation can influence stem cell transplant success in cancer patients

Immune cell transformation can influence stem cell transplant success in cancer patients

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have determined that a specific type of immune cell—type II innate lymphoid cells (ILC2s)—can change its characteristics and functions after a cancer patient receives stem cells from a donor, thereby preventing an effective, healthy rebuilding of the immune system. This new understanding of ILC2 cells’ transformational flexibility could lead to better strategies for enhancing immune system recovery post-transplantation.

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