Controlling thickness in fruit fly hearts reveals new pathway for heart disease

Scientists at Sanford Burnham Prebys and Salk Institute for Biological Studies have uncovered a new role for a protein known for its role in the brain helping control feelings of hunger or satiety, as well as in the liver to aid the body in maintaining a balance of energy during fasting. The new study shows that this protein also supports the maintenance of heart structure and function, but when it is overactive it causes thickening of the heart muscle, which is associated with heart disease.

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