For the first time, researchers have implicated the gene CHCHD2 in Huntington’s disease (HD)—an incurable genetic neurodegenerative disorder—and identified the gene as a potentially new therapeutic target. In a brain organoid model of the disease, the researchers found that mutations in the Huntington gene HTT also affect CHCHD2, which is involved in maintaining the normal function of mitochondria.
Medical Xpress – latest medical and health news stories
