Understanding the genetic roots of rare mutations in Alzheimer’s disease

Understanding the genetic roots of rare mutations in Alzheimer’s disease

Alzheimer’s disease is a debilitating condition that slowly robs people of their memory and cognitive abilities, affecting millions of people worldwide. Familial Alzheimer’s disease (FAD), a rare inherited form of the disease, is linked to mutations in several genes, including APP, PSEN1, and PSEN2. The impact of PSEN2 mutations has remained less understood—until now.

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